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KMID : 0383819890360030233
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Tuberculosis and Respiratory Diseases
1989 Volume.36 No. 3 p.233 ~ p.237
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Site of Bronchodilatation with Inhaled Fenoterol and Ipratropium Bromide in Bronchial Asthma
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오춘수/Chun Soo Oh
최인선/송창훈/김영철/김정일/양재범/박경옥/In Seon Choi/Chang Hoon Song/Young Chul Kim/Jung I1 Kim/Jae Beom Yang/Kyung Ok Park
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Abstract
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To assess site of action of bronchodilatation with a beta adrenergic agonist, fenoterol,
and an anticholinergic bronchodilator, ipratropium bromide, we measured the density
dependence of maximal expiratory flow rate in 37 asthmatics.
There were no significant changes in ΔVmax 50 with either agent. However, there
were significant inverse correlations between the prebronchodilator ΔVmax 50 and the
change in ΔVmax 50 after the administration of fenoterol or ipratropium.
These results suggest that sites of bronchodilatation in asthmatics are not different
between fenoterol and ipratropium, and those are related to the prebronchodilator site of
obstruction.
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